Objective To investigate the application value of local ffap transfer in defect repair after nasofacial tumor resection. Methods A total of 120 patients who underwent nasofacial tumor resection in Changzhou Jintan First People's Hospital from January 2022 to June 2025 were selected. According to the random number table method, they were divided into the control group and the observation group, with 60 patients in each group. The control group received free skin graft transplantation for defect repair, and the observation group received local ffap transfer for defect repair. The tissue survival and defect healing, appearance satisfaction, nasofacial function, scar condition in the repair area, and complications were compared between the two groups. Results The tissue survival rate and primary defect healing rate in the observation group were higher than those in the control group, and the average healing time was shorter than that in the control group (P<0.05). The appearance satisfaction rate in the observation group (96.67%) was higher than that in the control group (73.33%) (P<0.05). The nasofacial function score in the observation group was higher than that in the control group, and the VSS score was lower than that in the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group (P<0.05). Conclusion Compared with free skin graft transplantation, local ffap transfer for defect repair after nasofacial tumor resection can effectively improve tissue survival rate and defect healing rate, promote the recovery of nasofacial function, reduce the incidence of postoperative complications, and achieve higher appearance satisfaction after repair.