Objective To analyze the effect of orthodontics combined with oral restoration treatment on facial aesthetics in adult patients with malocclusion. Methods A total of 60 adult patients with malocclusion who were treated in the Department of Stomatology,the First Hospital in Weinan from January 2019 to August 2023 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 30 patients in each group. The control group received simple restoration treatment, and the observation group received orthodontics combined with oral restoration treatment. The facial aesthetics, treatment effect, occlusal function indexes, periodontal health indexes and complication rate were compared between the two groups. Results The score given by professional physicians and the self-assessment score of patients in the observation group were higher than those in the control group (P<0.05). The total effective rate of the observation group (96.67%) was higher than that of the control group (76.67%) (P<0.05). After treatment, the anterior overbite and overjet, excellent and good rate of molar relationship, and occlusal contact area in the observation group were better than those in the control group (P<0.05). After treatment, the GI, PD and AL in the observation group were lower than those in the control group (P<0.05). The incidence of complications in the observation group (3.33%) was lower than that in the control group (20.00%) (P<0.05). Conclusion Orthodontics combined with oral restoration exerts a favorable effect in adultpatients with malocclusion. It can effectively improve facial aesthetics, optimize occlusal function and periodontal health status, and help to reduce the incidence of complications. It is worthy of clinical application.