Objective To explore the effect of multi-target precise suspension scheme on facial aesthetic indicators and skin function indicators in patients undergoing small incision face lift surgery. Methods A total of 80 patients who underwent small incision face lift surgery in Beijing Huameiting Medical Beauty Clinic from January to December 2024 were selected. According to the different selection methods of suspension points, they were divided into the control group and the observation group, with 40 patients in each group. The control group received the traditional single-target suspension scheme (only the temporal region was selected as the suspension point), and the observation group received the multi-target precise suspension scheme. The facial aesthetic indicators, skin function indicators and complication rate were compared between the two groups. Results At 6 months after surgery, the scores of nasolabial fold depth and mandibular margin definition in the two groups were better than those before surgery, and those in the observation group were better than those in the control group (P <0.05). The improvement rate of facial laxity in the observation group was higher than that in the control group (P <0.05). At 6 months after surgery, the skin elasticity coefficient in the two groups was higher than that before surgery, and that in the observation group was higher than that in the control group (P <0.05). The incidence of complications in the observation group was 5.00%, lower than 15.00% in the control group, but the difference was not statistically significant (P >0.05). Conclusion The application of multi-target precise suspension scheme in patients undergoing small incision face lift surgery can more comprehensively improve facial aesthetic indicators, ameliorate facial laxity and skin elasticity, and has good safety, which is worthy of clinical application.