透明质酸敷料联合强脉冲光治疗对面部敏感性皮肤患者皮肤屏障功能的影响
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李思妮(1977.3-),女,广东广州人,本科,主治医师,主要从事皮肤美容方向的工作

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R751.05

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Effect of Hyaluronic Acid Dressing Combined with Intense Pulsed Light Therapy on Skin Barrier Function in Patients with Facial Sensitive Skin
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    摘要:

    目的 探讨透明质酸敷料联合强脉冲光(IPL)治疗对面部敏感性皮肤患者皮肤屏障功能的影响。方法 选取广州新漾悦容医疗美容诊所于2024年9月-2025年6月收治的102例面部敏感性皮肤患者,根据治疗方式不同分为对照组、观察组,每组51例。对照组采用透明质酸敷料外用治疗,观察组在对照组基础上联合IPL治疗,比较两皮肤屏障功能、皮肤敏感指数、皮肤状态参数、不良反应发生情况。结果 观察组治疗后TEWL、皮肤pH值均优于对照组(P<0.05);观察组治疗后瘙痒、刺痛、灼热和紧绷感评分均低于对照组(P<0.05);观察组治疗后凹陷指数、面部红斑面积及指数均低于对照组(P<0.05);观察组不良反应发生率(7.84%)低于对照组(15.69%),但差异无统计学意义(P>0.05)。结论 透明质酸敷料联合IPL治疗可有效改善面部敏感性患者的皮肤屏障功能及皮肤状态,减轻皮肤敏感症状,具有较好的安全性与耐受性。

    Abstract:

    Objective To explore the effect of hyaluronic acid dressing combined with intense pulsed light (IPL) therapy on skin barrier function in patients with facial sensitive skin. Methods A total of 102 patients with facial sensitive skin admitted to Guangzhou Xinyang Yuerong Medical Beauty Clinic from September 2024 to June 2025 were selected. According to different treatment methods, they were divided into the control group and the observation group, with 51 patients in each group. The control group received topical hyaluronic acid dressing, and the observation group received hyaluronic acid dressing combined with IPL therapy on the basis of the control group. The skin barrier function, skin sensitivity indexes, skin state parameters and adverse reactions were compared between the two groups. Results After treatment, the TEWL and skin pH value in the observation group were better than those in the control group (P<0.05). The scores of pruritus, stinging, burning and tightness in the observation group were lower than those in the control group (P<0.05). The depression index, facial erythema area and erythema index in the observation group were lower than those in the control group (P<0.05). The incidence of adverse reactions in the observation group (7.84%) was lower than that in the control group (15.69%), but the difference was not statistically significant (P>0.05). Conclusion Hyaluronic acid dressing combined with IPL therapy can effectively improve the skin barrier function and skin state of patients with facial sensitive skin, alleviate skin sensitive symptoms, and has good safety and tolerability.

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李思妮,李荣适,宋佳音.透明质酸敷料联合强脉冲光治疗对面部敏感性皮肤患者皮肤屏障功能的影响[J].医学美学美容,2025,34(24):41-45.

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  • 在线发布日期: 2026-01-22
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