Objective To explore the effect of autologous nasal septal cartilage transplantation combined with autologous auricular cartilage transplantation on tip rhinoplasty effect in patients undergoing tip rhinoplasty. Methods A total of 66 patients who underwent tip rhinoplasty in the Afffliated Hospital of Nantong University from October 2023 to April 2025 were selected, and they were divided into the reference group and the study group by the random number table method, with 33 patients in each group. The reference group was treated with expanded polytetraffuoroethylene implant augmentation, and the study group was treated with autologous nasal septal cartilage transplantation combined with autologous auricular cartilage transplantation. The clinical efffcacy, nasal tip height, tip rhinoplasty effect, complication rate and satisfaction with correction effect were compared between the two groups. Results The total effective rate of the study group (96.97%) was higher than that of the reference group (75.76%) (P<0.05). There was no statistically signiffcant difference in nasal tip height between the two groups (P>0.05). The scores of tip rhinoplastyeffect in the study group after treatment were all higher than those in the reference group (P<0.05). The incidence of complications in the study group (3.03%) was lower than that in the reference group (24.24%) (P<0.05). The satisfaction with correction effect in the study group was higher than that in the reference group (P<0.05). Conclusion In tip rhinoplasty, the combined application of autologous nasal septal cartilage and auricular cartilage transplantation can simultaneously improve the nasal tip shape, maintain the nasal tip height, reduce the risk of complications, and ultimately achieve more stable and reliable rhinoplasty effect and higher patient satisfaction.