In recent years, the demand for body management has shown a sharp upward trend, and the phenomenon of depression after aesthetic weight-loss behaviors has gradually become a hot topic in interdisciplinary research. In the early stage after successful body modification, individuals often experience a "honeymoon period" with enhanced self-efficacy. However, some individuals subsequently experience an emotional decline, and even fall into clinically diagnosable depression. This psychological process is phased: initially, the improvement of body image brings positive emotions, which then gradually diminish due to reduced social attention and increased pressure to maintain the result. Finally, some individuals develop depressive tendencies, manifested as negative reactions such as emotional regulation difficulties and reduced self-worth. To deeply explore the mechanism of depression in the population undergoing aesthetic weight-loss behaviors, this paper discusses the correlation between aesthetic weight-loss behaviors and depression, as well as the mechanism of concurrent depression after aesthetic weight-loss behaviors and clinical intervention methods, aiming to provide theoretical basis and practical guidance for clinical intervention.