Objective To analyze the effect of digital guide plate-assisted oral implant restoration on implant position accuracy and restoration satisfaction in patients with dentition defects. Methods A total of 93 patients with dentition defect who received oral implant restoration in Nanjing Jintai Dental Clinic from January to December 2024 were selected, and they were divided into the control group (n =46) and the study group (n =47) by the random number table method. The control group received conventional oral implant restoration, and the study group received digital guide plate-assisted oral implant restoration. The implant position accuracy, periodontal health, restoration satisfaction and aesthetic effect were compared between the two groups. Results At 6 months after restoration, the neck deviation in the buccolingual direction, apical deviation in the buccolingual direction, neck deviation in the vertical direction, and apical deviation in the vertical direction of the study group were smaller than those of the control group (P <0.05). At 6 months after restoration, the scores of PLI, GI and SBI in the study group were lower than those in the control group (P <0.05). The restoration satisfaction rate of the study group (95.74%) was higher than that of the control group (82.61%) (P <0.05). At 6 months after restoration, the scores of PES and WES in the study group were higher than those in the control group (P <0.05). Conclusion Digital guide plate-assisted oral implant restoration can effectively improve the implant position accuracy and restoration satisfaction of patients with dentition defect, and also help to improve periodontal health and achieve better aesthetic effect.