Objective: To explore the application effect of Cameron"s Timing Theory combined with sequential nursing in patients undergoing facial burn scar plastic surgery. Methods: A total of 110 patients undergoing facial burn scar plastic surgery admitted to our hospital from May 2023 to May 2025 were selected and divided into two groups with 55 cases each according to the random number table method. The control group received routine nursing, and the observation group received Cameron"s Timing Theory combined with sequential nursing. The scar condition, negative emotions, complications and quality of life were compared between the two groups. Results: There was no significant difference in scar condition between the two groups before nursing (P>0.05). After nursing, the improvement of the observation group was better than that of the control group (P<0.05). There was no significant difference in negative emotions between the two groups before nursing (P>0.05). After nursing, the improvement of the observation group was more significant (P<0.05). The total complication rate of the observation group was 9.09%, which was lower than 29.09% of the control group (P<0.05). There was no significant difference in quality of life between the two groups before nursing (P>0.05). After nursing, the improvement of the observation group was better (P<0.05). Conclusion: The application of Cameron"s Timing Theory combined with sequential nursing in patients undergoing facial burn scar plastic surgery can improve scar condition and negative emotions, reduce complications and improve quality of life.Keywords: Facial burns; Scar plastic surgery; Cameron"s Timing Theory; Sequential nursing