Objective: To investigate the impact of health promotion-based nursing interventions on psychological distress and aesthetic outcomes in dental implant patients. Methods: A total of 126 dental implant patients from April 2024 to May 2025 were enrolled at Nanjing Medical University Affiliated Stomatological Hospital (Jiangsu Provincial Stomatological Hospital). Participants were randomly assigned to two groups (63 cases each) using the sealed envelope method. The control group received standard nursing care, while the intervention group underwent health promotion-based nursing interventions. Comparative assessments were conducted on psychological distress [Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)], nursing satisfaction, aesthetic outcomes [Perceived Esthetic Score (PES)], and quality of life [SF-36 Quality of Life Scale]. Results: After 3 months of intervention, the intervention group achieved a SAS score of 45.72±3.69 and SDS score of 39.38±4.27, significantly lower than the control group"s 50.62±3.47 and 43.63±3.54 scores (P<0.05). The intervention group demonstrated significantly lower psychological distress scores (P<0.05) and higher nursing satisfaction rates compared to the control group (P<0.05). Both groups showed statistically significant improvements in aesthetic outcomes (P<0.05) and SF-36 scores (P<0.05) after 3 months of intervention. Conclusion: Health promotion-based nursing interventions systematically improved psychological distress, nursing satisfaction, and aesthetic outcomes in dental implant patients through multidimensional strategies, thereby enhancing quality of life.