医用重组胶原蛋白复合溶液敷料对植发术后创面愈合时间的影响
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广西壮族自治区人民医院

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    摘要:

    摘要:目的:探讨医用重组胶原蛋白复合溶液敷料在促进植发术后创面愈合 中的作用,提供有利于毛囊生长的微环境,促进毛囊植发术后创面愈合,并从多维角度评价其临床效果。方法:选取2023年1月至2024年12月在本院接受植发手术的80例患者,随机分为观察组和对照组,各40例。对照组术后采用常规护理,观察组在此基础上使用医用重组胶原蛋白复合溶液敷料。比较两组创面愈合时间、感染率、瘢痕各维度评分及满意度。结果: 观察组愈合时间为(7.48±1.21)d,短于对照组(9.07±1.36)d(P<0.001);感染率分别为2.50%和12.50%(P=0.042)。术后6个月Vancouver瘢痕评分各维度中,观察组颜色(0.86±0.42)、厚度(1.02±0.51)、柔软度(0.98±0.47)、血管扩张(1.06±0.49)均低于对照组(1.42±0.53、1.55±0.57、1.48±0.61、1.63±0.58),差异均有统计学意义(P<0.05)。术后12个月满意度观察组为(8.43±0.97)分,对照组为(7.12±1.28)分(P<0.001)。结论:医用重组胶原蛋白复合溶液敷料提供有利于毛囊生长的微环境,促进毛囊植发术后创面愈合,降低感染率,改善瘢痕外观并提高患者满意度,具有良好的安全性和临床应用价值。

    Abstract:

    The influence of medical recombinant collagen composite solution dressing on the healing time of postoperative wound of hair transplantation Jiang Minmin (Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 53002, China) [Abstract]Objective To explore the role of medical recombinant collagen composite solution dressing in promoting the healing of post wounds of hair transplantation, providing a microenvironment conducive to hair follicle growth, promoting the healing of postoperative wounds of hair follicle transplantation, and its clinical effect from a multi-dimensional perspective. Methods A total of 280 patients who underwent hair transplantation surgery in our hospital from June 2023 to 2025 were selected and divided into control group and observation group according to the randomized numerical table method, with 140 cases in each group. Both groups implemented unified postoperative local treatment scheme, including cleaning the hair transplantation area with 0.9% normal saline injection solution and applying mupirocin ointment topically prevent infection; the observation group was treated with medical recombinant collagen composite solution dressing on this basis, and used it continuously for 5 to 7 days. The time wound healing, scabbing, scab shedding, redness/swelling subsidence, postoperative infection rate, patient satisfaction and comprehensive efficacy were compared between the two groups. The observation group was superior to the control group in all aspects of wound repair indicators, with a wound healing time of (7.48±1.21) days,abbing time of (3.95±0.86) days, scab shedding time of (9.78±1.28) days, andness/swelling subsidence time of (5.14±0.92) days, all of which were shorter than those of the control group [(9.0±1.36) days, (4.82±0.97) days, (11.56±1.45) days, (632±1.14) days] (P < 0.001). The infection rate in the observation group was 2.50%, was lower than that in the control group (12.50%) (P = 0.042); the patient satisfaction score was (8.43±.97) points, which was higher than that in the control group [(7.12±1.28) points] (P < 0.001 In terms of comprehensive efficacy, the total effective rate in the observation group was 97.50%, which was higher than that in the control group (85.0%) (P = 0.043). Conclusion Medical recombinant collagen composite solution dressing provides a microenvironment conducive to hair follicle, promotes the healing of postoperative wounds of hair follicle transplantation, reduces the infection rate, improves the appearance of scars and improves patient satisfaction, and has good safety and application value. ? [Keywords] Recombinant collagen; Composite solution dressing; Post-transplantation; Wound healing; Microenvironment

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  • 收稿日期:2025-10-31
  • 最后修改日期:2026-03-09
  • 录用日期:2026-03-10
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