杨正文（1979.12-），女，贵州凯里人，本科，主治医师，主要从事医学美容临床工作
R322.99
目的 研究755 nm皮秒激光仪联合rhEGF对松弛型毛孔粗大患者毛孔粗大改善程度的影响。方法 选 取2023年1月-7月我院接诊的83例松弛型毛孔粗大患者为研究对象，采用随机数字表法分为对照组（42例）和 研究组（41例）。对照组采用755 nm皮秒激光仪治疗，研究组采用755 nm皮秒激光仪+rhEGF治疗，比较两组临 床疗效、毛孔粗大改善程度评分、毛孔数量、不良反应发生率、治疗满意度。结果 研究组治疗总有效率 （95.12%）高于对照组（76.19%），差异有统计学意义（P＜0.05）；两组治疗第1、2、3、4次后毛孔粗大改 善程度评分比较，差异无统计学意义（P ＞0.05），研究组治疗第5次后毛孔粗大改善程度评分低于对照组， 差异有统计学意义（P ＜0.05）；两组治疗后毛孔数量均少于治疗前，且研究组少于对照组（P ＜0.05）； 研究组不良反应发生率（4.88%）低于对照组（23.81%），差异有统计学意义（P ＜0.05）；研究组治疗 满意度（97.56%）高于对照组（85.71%），差异有统计学意义（P ＜0.05）。结论 755 nm皮秒激光仪 +rhEGF治疗松弛型毛孔粗大可获得理想的治疗效果，降低不良反应发生率，改善毛孔可见度和粗大程 度，提升治疗满意度。
Objective To study the effect of 755 nm picosecond laser device combined with rhEGF on enlarged pores improvement in patients with relaxed enlarged pores. Methods A total of 83 patients with relaxed enlarged pores admitted to our hospital from January to July 2023 were selected as the research subjects. According to the random number table method, they were divided into the control group (42 patients) and the study group (41 patients). The control group was treated with 755 nm picosecond laser device, and the study group was treated with 755 nm picosecond laser device combined with rhEGF. The clinical efficacy, enlarged pores improvement score, pores number, adverse reactions and treatment satisfaction were compared between the two groups. Results The total effective rate of treatment in the study group (95.12% ) was higher than that in the control group (76.19%), and the difference was statistically significant (P <0.05). There was no significant difference in the score of enlarged pores improvement between the two groups after the 1st, 2nd, 3rd, and 4th treatments (P >0.05), and the score of enlarged pores improvement in the study group after the 5th treatment was lower than that in the control group, and the difference was statistically significant (P <0.05). The number of pores in the two groups after treatment was less than that before treatment, and that in the study group was less than that in the control group (P <0.05). The incidence of adverse reactions in the study group (4.88%) was lower than that in the control group (23.81%) , and the difference was statistically significant (P <0.05). The treatment satisfaction rate in the study group (97.56%) was higher than that in the control group (85.71%), and the difference was statistically significant (P <0.05). Conclusion 755 nm picosecond laser+rhEGF in the treatment of relaxed enlarged pores can achieve an ideal treatment effect, reduce the incidence of adverse reactions, improve the visibility and enlargement of pores, and enhance the treatment satisfaction.
杨正文.755 nm皮秒激光仪联合rhEGF对松弛型毛孔粗大患者毛孔粗大改善程度的影响[J].医学美学美容,2025,34(8):77-81.
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