微针注射胶原蛋白及氨甲环酸治疗对黄褐斑患者MASI评分的影响
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作者简介:

丁娜娜(1981.5-),女,河南项城人,本科,主治医师,主要从事损容性皮肤病诊治工作

通讯作者:

郑罡(1972.11-),男,江西玉山县人,硕士,主任医师,主要从事损容性疾病、面部年轻化诊治工作

中图分类号:

R758.4+2


Effect of Microneedle Injection of Collagen and Tranexamic Acid Treatment on MASI Score in Patients with Melasma
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    摘要:

    目的 研究微针注射胶原蛋白及氨甲环酸治疗对黄褐斑患者MASI评分的影响。方法 选取 2023年5月-2024年5月东南大学医院附属徐州医院皮肤科收治的70例黄褐斑患者为研究对象,按随机 数字表法分为对照组和观察组,每组35例。对照组行微针注射氨甲环酸治疗,观察组行微针注射胶原 蛋白联合氨甲环酸治疗,比较两组面部图像分析参数、MASI评分及不良反应发生情况。结果 与对照组 相比,观察组面部图像分析参数的改善程度更优(P <0.05);观察组治疗后MASI评分为(5.79±2.68) 分,优于对照组的(7.97±2.43)分(P <0.05);与对照组不良反应发生率(25.71%)相比,观察组不 良反应发生率(5.71%)更低(P<0.05)。结论 黄褐斑患者经过微针注射胶原蛋白联合氨甲环酸治疗,其 面部改善效果明显,可有效改善黄褐斑面积和严重程度,降低不良反应发生率,值得临床应用。

    Abstract:

    Objective To study the effect of microneedle injection of collagen and tranexamic acid on MASI score in patients with melasma. Methods A total of 70 patients with melasma admitted to the Department of Dermatology, Xuzhou Central Hospital Affiliated to Medical School of Southeast University from May 2023 to May 2024 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 35 patients in each group. The control group was treated with microneedle injection of tranexamic acid, and the observation group was treated with microneedle injection of collagen combined with tranexamic acid. The facial image analysis parameters, MASI score and adverse reactions were compared between the two groups. Results Compared with the control group, the improvement degree of facial image analysis parameters in the observation group was better (P <0.05). The MASI score in the observation group after treatment was (5.79±2.68)scores, which was better than (7.97±2.43)scores in the control group (P <0.05). Compared with the incidence of adverse reactions in the control group (25.71%), the incidence of adverse reactions in the observation group (5.71%) was lower (P <0.05). Conclusion For patients with melasma, treatment with microneedle injection of collagen combined with tranexamic acid has an obvious facial improvement effect. It can effectively improve the area and severity of melasma and reduce the incidence of adverse reactions, which is worthy of clinical application.

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丁娜娜,郑罡,徐晶晶.微针注射胶原蛋白及氨甲环酸治疗对黄褐斑患者MASI评分的影响[J].医学美学美容,2025,34(8):61-64.

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  • 在线发布日期: 2025-05-26