A型肉毒素注射联合透明质酸填充在面部除皱中的应用
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张越越(1985.11-),女,江苏南京人,本科,主治医师,主要从事整形注射方面工作

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R622


Application of Type A Botulinum Toxin Injection Combined with Hyaluronic Acid Filling in Facial Wrinkle Reduction
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    摘要:

    目的 研究A型肉毒素注射联合透明质酸填充应用在面部美容除皱中的效果。方法 选择2023年 1月-2024年6月于南京美贝尔美容医院进行面部除皱的82名女性,按照随机数字表法分为对照组(40名) 和观察组(42名)。对照组实施透明质酸填充,观察组在对照组的基础上联合A型肉毒素注射,比较两组 VISIA特征评分、皮肤弹性与皮肤紧致度、不良反应发生情况。结果 观察组紫质、毛孔、纹理、皱纹、色 素斑评分低于对照组,差异有统计学意义(P <0.05);观察组治疗后皮肤弹性、皮肤紧致度评分高于对照 组,差异有统计学意义(P <0.05);观察组不良反应发生率为4.76%,低于对照组的10.00%,但差异无统 计学意义(P >0.05)。结论 将 A型肉毒素注射联合透明质酸填充应用在面部除皱中,相较于单纯应用透 明质酸填充能更好地提升除皱效果,提高面部美观度,且不会增加不良反应发生几率。

    Abstract:

    Objective To study the application effect of type A botulinum toxin injection combined with hyaluronic acid filling in facial wrinkle reduction. Methods A total of 82 females who underwent facial wrinkle reduction in Nanjing Mebel Beauty Hospital from January 2023 to June 2024 were selected. According to the random number table method, they were divided into the control group (40 females) and the observation group (42 females). The control group was treated with hyaluronic acid filling, and the observation group was combined with type A botulinum toxin injection on the basis of the control group. The VISIA characteristic scores, skin elasticity, skin tightness and adverse reactions were compared between the two groups. Results The scores of purpura, pore, texture, wrinkle and pigmentation in the observation group were lower than those in the control group, and the differences were statistically significant (P <0.05). After treatment, the scores of skin elasticity and skin tightness in the observation group were higher than those in the control group, and the differences were statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 4.76%, which was lower than 10.00% in the control group, but the difference was not statistically significant (P >0.05). Conclusion The application of type A botulinum toxin injection combined with hyaluronic acid filling in facial wrinkle reduction can better improve the wrinkle reduction effect and enhance the facial aesthetics compared with the simple application of hyaluronic acid filling, and it will not increase the incidence of adverse reactions.

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张越越. A型肉毒素注射联合透明质酸填充在面部除皱中的应用[J].医学美学美容,2025,34(8):45-48.

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  • 在线发布日期: 2025-05-26